In a recent article in the US Pharmacist, Dr Christine Lin PhD from the The George Institute for Global Health, commented:
"Unfortunately there are no drugs proven to work for people with sciatica and even epidural injections only provide a small benefit in the short term."
This comment was in response to results, published recently in the New England Journal of Medicine, that found the drug Pregabalin, marketed as Lyrica, was shown in the study to be no better than placebo, and that taking the medication doubled your chances of experiencing other symptoms such as dizziness.
So if you are taking Lyrica or Pregabalin for sciatica you shouldn't be, it doesn't work. Dr Christine Lin urged prescribers to note the findings and seek alternative ways of managing and preventing pain.